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Human Metapneumovirus (HMPV): A Respiratory Threat for Elderly and Children’s

Home > Blog > Human Metapneumovirus (HMPV): A Respiratory Threat for Elderly and Children’s

HMPV virus written on a paper

Monday, 13 January, 2025

The respiratory virus known as Human Metapneumovirus (HMPV), which belongs to the Pneumoviridae family, can cause everything from mild colds to severe lung infections such as pneumonia and bronchiolitis. Although less well-known than COVID-19 or influenza, HMPV poses an acute respiratory risk to people all around the world. The recent HMPV virus in China has raised international concerns, highlighting the potential severity of outbreaks in various regions. 

While most HMPV virus cases are mild and self-limiting, they can lead to serious complications in vulnerable groups such as young children, the elderly, pregnant women, and those with weakened immune systems.

The recent HMPV virus in Bangalore has raised concerns, as it affects these high-risk individuals, highlighting significance of awareness and preventative actions. Let’s delve into HMPV virus , its symptoms, treatment options, and effective prevention strategies to help you stay informed and protected.

What is Human Metapneumovirus (HMPV)?

Human Metapneumovirus (HMPV) is a respiratory virus first identified in 2001, though it has been circulating worldwide since the 1970s. As a member of the Pneumoviridae family, HMPV primarily targets the respiratory system. Raising awareness and ensuring early discovery is essential for effective care because its symptoms frequently resemble those of other respiratory illnesses.

HMPV cases in India typically peak during the cooler months, from November to May. During these months, both adults and children should adopt preventive measures to reduce the risk of infection

How Does HMPV Virus Spread?

HMPV spreads through respiratory droplets and contaminated surfaces, making close-contact environments particularly susceptible.

  • Coughing and Sneezing: Infectious droplets from an infected person enter the air.
  • Surface Contact: Touching contaminated objects and then touching the mouth, nose, or eyes.
  • Close Interactions: Extended physical proximity with infected individuals increases the likelihood of transmission.

Who is Most at Risk of HMPV Virus?

HMPV can affect anyone, but certain populations are more vulnerable:

  • Young Children: Infants and toddlers are particularly susceptible to severe respiratory conditions such as bronchiolitis and pneumonia.
  • Older Adults: People aged 65 and above or those with chronic conditions like asthma or COPD are at higher risk of complications.
  • Pregnant Women: Respiratory infections during pregnancy can pose risks to both the mother and the baby.
  • Immunocompromised Individuals: Those undergoing treatments like chemotherapy or living with chronic illnesses may experience more severe symptoms.

Woman giving an inhalation to baby

Symptoms of HMPV Virus in Adults and Children

HMPV symptoms in adults often resemble those of a common cold or flu. They include:

  • Runny nose or nasal congestion
  • Sore throat and dry cough
  • Fever, typically mild to moderate
  • Fatigue and general body aches
  • Shortness of breath in severe cases

For adults with compromised immunity or underlying health conditions, HMPV may escalate to severe respiratory complications like pneumonia.

Children are more likely to experience severe signs and symptoms of HMPV virus, including:

  • Persistent cough and wheezing
  • Difficulty breathing or rapid/shallow breaths
  • High fever and irritability
  • Poor feeding habits in infants

Parents should pay close attention to sign of respiratory distress in children and seek medical care promptly if symptoms worsen.

image showing hmpv symptoms

How is HMPV Virus Detected?

Accurate diagnosis is essential to distinguish HMPV from other respiratory infections. Methods include:

  • PCR Tests: Molecular testing to detect the virus's genetic material.
  • Rapid Antigen Tests: Faster but less sensitive compared to PCR.
  • Bronchoscopy: Used in severe cases to assess airway conditions.

PCR Coronavirus rapid test

Differences Between HMPV and COVID-19

While HMPV and COVID-19 are both respiratory illnesses, they differ significantly in their impact and behavior.

Feature HMPV COVID-19
Severity Mild to moderate symptoms in most cases Can involve severe systemic complications
Target Groups Primarily affects children, elderly, and immunocompromised Broad impact across all age groups
Transmission Rate Less contagious Highly contagious
Symptoms Primarily respiratory Multi-system involvement
Treatment Supportive care only Antiviral medications and vaccines available

Understanding these differences helps in managing outbreaks effectively.

Treatment for HMPV virus Adults and Children

Currently, no specific antiviral drug or vaccine is available for HMPV, and treatment focuses on managing symptoms.

For Adults:

  • Over-the-counter medications like antipyretics for fever and antihistamines for nasal congestion.
  • Rest and hydration to ease recovery.
  • Oxygen therapy or hospitalization in severe cases, especially for elderly or immunocompromised individuals.
  • No specific antiviral although Ribavirin is used in some cases.

For Children:

  • Nebulization therapy for breathing difficulties.
  • Pediatric antipyretics to manage fever.
  • Hospitalization for infants or children showing signs of severe respiratory distress.

Parents are encouraged to consult a paediatrician for personalized care plans.

Preventive Measures for HMPV Virus in Adults and Children

Since no targeted therapy exists for HMPV, prevention remains the most effective strategy.

HMPV virus prevention in adults

  • Practice good hand hygiene by washing hands frequently with soap & water for at least 30 seconds or using alcohol-based hand sanitizers
  • Avoid close contact with individuals showing symptoms of respiratory illness.
  • Wear masks in crowded or poorly ventilated spaces.
  • Stay home if experiencing symptoms to prevent spreading the virus.

HMPV virus prevention in Children

  • Encourage children to wash their hands regularly, especially after school or playtime.
  • Teach proper cough etiquette, such as covering the mouth and nose while sneezing or coughing.
  • Ensure frequently touched objects like toys are cleaned and disinfected regularly.

For families, maintaining a clean environment and limiting exposure during peak respiratory illness seasons can significantly reduce the risk.

Complications Associated With HMPV Virus

Most individuals recover within 7-10 days, but complications can occur, especially in vulnerable groups.

  • Pneumonia: Severe lung infections requiring hospitalization.
  • Bronchiolitis: Inflammation and blockage of airways, particularly in young children.
  • Exacerbation of Chronic Conditions: Worsening of asthma or COPD symptoms.
  • Secondary Infections: Bacterial infections like pneumonia may arise.
  • Pregnancy Risks: Respiratory issues can affect both maternal and fetal health.

image of pneumonia affecting lungs

How does HMPV Affects Individuals with Co-existing Conditions

For individuals with co-existing conditions such as diabetes, heart disease, chronic obstructive pulmonary disease (COPD), kidney disease, cancer, or those undergoing dialysis, HMPV can have more severe effects. These individuals may have weakened immune systems, making it harder for their bodies to fight off infections. However, with the right precautions, these risks can be managed effectively.

Other conditions such as asthma or liver disease can also contribute to heightened risks, but with proper care, individuals with these conditions can still take steps to protect themselves from complications. For these high-risk groups, HMPV may escalate from mild symptoms to more serious conditions, but by following preventive measures and seeking timely medical attention, the impact can be minimized.

Why Raising Awareness About HMPV Virus Is Crucial

HMPV virus might not be as widely discussed as other respiratory viruses, but its impact on vulnerable groups cannot be ignored. Awareness ensures timely diagnosis, appropriate treatment, and adherence to preventive measures.

Both children and adults can significantly benefit from understanding how to protect themselves and others from this virus.

Conclusion

Human metapneumovirus is not a new virus in India, but its potential impact on both adults and children warrants attention. While most cases are mild, vulnerable groups like young children and older adults may face complications.

By following government protocols, maintaining hygiene, and seeking timely medical care, we can minimize the spread and impact of HMPV in our communities. Whether for yourself, your children, or elderly family members, staying informed is the first step to staying healthy. If you're in need of specialized care, consulting a pulmonologist in Bangalore can help manage any respiratory symptoms and ensure proper treatment.

FAQs

What is HMPV virus?

HMPV (Human Metapneumovirus) is a respiratory virus that belongs to the Pneumoviridae family. It causes infections ranging from mild cold-like symptoms to more severe respiratory conditions such as pneumonia and bronchiolitis.

Can HMPV virus cause death?

HMPV typically causes mild symptoms like a cold or flu, with a very low case mortality rate. However, in high-risk individuals such as the elderly, young children, and those with weakened immune systems, it can lead to severe respiratory complications, which may be life-threatening in rare cases.

What are the common symptoms of HMPV in children?

Common symptoms of HMPV in children include a persistent cough, wheezing, difficulty breathing, high fever, irritability, and poor feeding habits in infants.

How is HMPV Virus transmitted?

HMPV is primarily transmitted through respiratory droplets when an infected person coughs, sneezes, or breathes. It can also spread by touching contaminated surfaces and then touching the nose, mouth, or eyes, making close contact environments particularly susceptible.

How long does it take to recover from HMPV?

Most individuals recover from HMPV within 7 to 10 days, as the virus typically causes mild symptoms similar to a cold or flu. However, recovery time may vary depending on the severity of symptoms and the individual’s overall health.

Is there a vaccine for HMPV (Human Metapneumovirus)?

No specific antiviral treatment for HMPV (Human Metapneumovirus), although Ribavirin is used in some cases. There is no specific vaccine currently, although research is in progress.

When should I get tested for HMPV?

You should get tested for HMPV if you or your child experience respiratory symptoms such as cough, fever, or difficulty breathing. Testing is especially important if you have underlying health conditions or if symptoms worsen or do not improve within a few days.

Author Doctor
Dr Sachin

Consultant Clinical and Interventional Pulmonology, Critical care and sleep disorders

MBBS (Gold Medal), MD (Pulmonary Medicine), DNB (Respiratory Medicine), DM (AIIMS, New Delhi-Pulmonology, Critical Care & Sleep Disorders), MNAMS, FCCP (USA), EDRM (Switzerland), FAPSR (Japan)

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